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CAH Volunteers Needed for Exercise Study
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Catecholamine Reserve and Exercise Tolerance in Subjects with CAH and in Healthy Controls Principal Investigator: Dr. Deborah Merke M.D., Pediatric Endocrinologist and Chief of Pediatric Services at NIH At the National Institutes of Health in Bethesda, Maryland, we are currently investigating the effects of sustained exercise over 90 minutes in patients with classic CAH. Participants will be paid $300 upon completion of the study. In order to participate in this study volunteers must: P have the classic form of CAH (21-hydroxylase deficiency);P be between 12 to 22 years old; P demonstrate good clinical control defined by: 17-OH-progesterone level between 100 and 1500 ng/dl, plasma renin activity within the normal reference range, normal growth rate (children), and no new signs of excess androgens; P not be on other medications besides their CAH-related medications. The study consists of 4 visits over 5 days and includes a screening visit (physical examination, family history, pregnancy test, and electrocardiogram), an exercise test to obtain fitness level, and two 90-minute standardized exercise tests. Travel is paid by the NIH. For more information or to volunteer, please contact Julie Hardin at (301) 496-6909.
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